Yang, Chen-Chung

Yang, Chen-Chung. "Crystallization and Properties of the Cobrotoxin from Formosan Cobra Venom." The Journal of Biological Chemistry 240 (1965) 1616-18. 

For many who study the chemistry of venoms, the neurotoxins hold particular interest. One example would be the polypeptide toxin cobrotoxin that was isolated from the Formosan cobra and analyzed in 1965 by Chen-Chung Yang, a distingmshed chair professor at Tsing Hua University in Taiwan. The primary structure of this neurotoxin is indicated in Figure 1, along with some components of its secondary structure. There are sixty-two residues in the primary structure and four di-sulfide bonds in the secondary structure. If even one of these di-sulfide bonds is somehow disrupted, the polypeptide is rendered nontoxic. This points to the fact that secondary structure is important even in small polypeptides, not only full-size proteins. 

Chung TW, Yang MC, Tseng CC, Sheu SH, Wang SS, Huang YY, Chen SD (2011) Biomaterials 32 734... 

Chih-Hang Chu, Yu-Chao Wang, Hsin-Ying Huang, Li-Chen Wuand Chung-Shi Yang. 

Tsai JH, Yang P, Chen CC, Chung W, Tang TC, Wang SY, Liu JK. Zolpidem-induced amnesia and somnambulism Rare occurrences Eur Neuropsychopharmacol 2009 19(1) 74-6. 

Xu H, Wu J, Chen C-H, Zhang L, Yang K-L (2010) Detecting hydrogen sulfide by using transparent polymer with embedded CdSe/CdS quantum dots. Sens Actuators B 143 535-538 Yu JY, Chung SW, Heath JR (2000) Silicon nanowires preparation, device fabrication, and transport properties. J Phys... 

Lu HF, Hsueh SC, Yu FS, Yang JS, Tang NY, Chen SC, Chung JG (2006) The role of Ca2-l- in (-)-menthol-induced human promyelocytic leukemia HL-60 cell death. In Vivo 20 69... 

Chang-Chung Yang, Kuo Huang Hsieh and Wen-Chang Chen (2003) "A new interpretation of the kinetic model for the imidization reaction of PMDA-ODA and BPDA-PDA poly(amic acid)s". In Polyimides and Other High Temperature Polymers, Vol. 2. K.L. Mittal editor. VSP. pp. 37-45. 

Chung, C. A., C. W. Yang, and C. W. Chen. 2006. Analysis of cell growth and diffusion in a scaffold for cartilage tissue engineering. Biotechnol Bioeng 94 1138-1146. 

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