Yamada glass cell method

H. Yamada, in Glass Cell Method for High-Pressure, High-Resolution NMR Measurements. Applications to the Studies of Pressure Effects on Molecular Conformation and Structure, Ed. 

The Streamline flow cell was connected to a glass-lined 500-gal vessel via a recycle loop as shown in Figure 22.1. A Yamada pump (1/2" pump with Kynar internals) was used to circulate the reaction solution from the vessel through Mettler Toledo s Streamline flow cell and back to the vessel via the above surface line. The process lines (3/8" JIC) composing the recycle loop were partially insulated, but not heat traced, resulting in a temperature drop between the vessel and the return line. Although the temperature at the probe was approximately 10°C lower than the batch temperature, the probe temperature did not fluctuate substantially once the temperature in the vessel reached a steady state. This temperature difference did not adversely affect the reaction yield, cycle time, or method development. 

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