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Y-vinyl GABA

Aamino-5-hexenoic acid 4-Aminohex-5-enoic acid y-Vinyl-y-aminobutyric acid y-Vinyl-GABA... [Pg.310]

VGAT Majority of interneurons of the CNS A- and B-cells of islets of Langerhans GABA (Km - 5 mM) Glycine (Km >10 mM) Nipecotic acid y-vinyl-GABA fi-alanine... [Pg.85]

Loscher, W. 1979. GABA in plasma and cerebrospinal fluid of different species. Effects of y-acetylenic GABA, y-vinyl GABA and sodium valproate. J. Neurochem. 32 1587-91. [Pg.56]

Inhibition of enzymatic breakdown of GABA GABA transaminase catalyzes pyridoxal-dependent transamination of GABA to succinic semialdehyde. The enzyme can be inhibited by a variety of compounds [e.g., y-vinyl GABA (Vigabatrin)]. [Pg.280]

Jung M. J, Lippert B., Metcalf B. W., Bohlen P., and Schlechter P J (1977a) y-Vinyl-GABA (4-aminohexionic acid), a new selective irreversible inhibitor of GABA-T Effects on brain GABA metabolism in mice. /. Neurochem 29, 797-802... [Pg.230]

Treatment has been attempted with y-vinyl GABA (vigabatrin, Sabril ), an inhibitor of GABA transaminase, in order to reduce substrate accumulation [6]. This resulted in a decrease of CSF y-hydroxybutyric acid levels and improvement of cerebellar signs in a majority of patients. [Pg.124]

See other pages where Y-vinyl GABA is mentioned: [Pg.129]    [Pg.1283]    [Pg.233]    [Pg.337]    [Pg.339]    [Pg.347]    [Pg.634]    [Pg.455]    [Pg.89]    [Pg.121]    [Pg.123]    [Pg.92]    [Pg.3425]    [Pg.2166]    [Pg.246]    [Pg.246]    [Pg.247]    [Pg.129]    [Pg.1283]    [Pg.290]    [Pg.291]    [Pg.36]    [Pg.743]    [Pg.159]    [Pg.215]    [Pg.216]    [Pg.217]    [Pg.217]    [Pg.218]    [Pg.219]    [Pg.13]   
See also in sourсe #XX -- [ Pg.438 ]

See also in sourсe #XX -- [ Pg.88 , Pg.121 ]



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