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Xanthotoxin 8-methoxypsoralen

Quinolone (antibacterial) Oral Xanthotoxin (8-methoxypsoralen) Oral, ip, im... [Pg.393]

Figure 2. Major metabolites of xanthotoxin (8-methoxypsoralen) in last-stage larvae of the black swallowtail butterfly (Papilio polyxenes) and the fall armyworm (Spodoptera frugiperda). Figure 2. Major metabolites of xanthotoxin (8-methoxypsoralen) in last-stage larvae of the black swallowtail butterfly (Papilio polyxenes) and the fall armyworm (Spodoptera frugiperda).
Methoxsalen (xanthotoxin 8-methoxypsoralen) (Figure 4.36), a constituent of the fruits of Ammi majus (Umbelliferae/Apiaceae), is used medically to facilitate skin repigmentation where severe blemishes exist (vitiligo). An oral dose of methoxsalen is followed by long wave UV irradiation, though such treatments must be very carefully regulated to... [Pg.146]

Methoxsalen. 9-Methoxy-7H-furo[3,2-g][i]-benZOpyran -7-one 6-hydroxy-7-methoxy-S-benzofuranacryt-ic acid 5.lactone 9-methoxypSOralen 8-methoxy-4, 5 6.7-furocoumartn 8-methoxy[furano-3, 2 6,7 -coumarm] ammoidin xanthotoxin 8-methoxypsoralen 8-MOP 8-MP Metadinine Meloxine Methoxa-Dome Oxsoralen Ultra Psoralon-MOP. f O, mot wt 216.18. C 66.67%,... [Pg.945]

Therapeutic Function Dermal pigmentation enhancer Chemical Name 9-methoxy-7H-furo[3,2-g] [1 ] benzopyran-7-one Common Name 8-Methoxypsoralen ammoidin xanthotoxin Structural Formula ... [Pg.987]

Bull, D.L., Ivie, G.W., Beier, R.C., and Pryor, N.W., In vitro metabolism of a linear furanocoumarin (8-methoxypsoralen, xanthotoxin) by mixed-function oxidases of larvae of black swallowtail butterfly and fall army worm, /. Chem. Ecol., 12,885,1986. [Pg.168]

The treatment of the allyl derivative with ozone has been advantageously replaced by the osmium tetroxide-KIO method psoralene has thus been made from a 7-acetoxy-6-alkylcoumarin and xanthotoxin, angelicin (28), and dehydrodemethoxyelliptone (114)3i3([ijbenzopyrano[3,4-6]furo[2,3-fe][l]benzopyran-6-one),thefuro-flavones and furoisoflavones, khellin (26), the angular furoxan-thone (115), and bergaptene (4-methoxypsoralene) have all been synthesized. [Pg.378]

Methoxypsoralen (Methoxsalen) See xanthotoxin in Miscellaneous Compounds in Chapter 6. [Pg.408]

Bergapten (5-methoxypsoralen) [484-20-8] M 216.2, m 190-193 , 191-193. Crystallise it from EtOH or aqueous MeOH, and it sublimes in vacuo. Its properties are similar to those of its 9-methoxy isomer (xanthotoxin, see below). It is slightly soluble in C6H6, CHCI3 and AcOH but insoluble in H2O. Its fluorescence has A,ex at 352nm with X,em at 480nm. It is a DNA intercalator and possible carcinogen. [Howell Robertson J Chem Soc 293 1937, Boyer et al. Biochemistry 27 3011 1988, Beilstein 19/6 V 4.]... [Pg.668]

Xanthotoxin (Methoxalen, 9-methoxypsoralen, Ammoidin, 9-methoxyfuro[3,2-g][l]benzopyran-7-one)... [Pg.906]

These furocoumarins are phototoxic compounds which cause phototoxic dermatitis. Many plants of the Apiaceae (Umbelliferae) and most of the Rutaceae contain 5-methoxypsoralen (bergapten) and 8-me-thoxypsoralen (xanthotoxin). Their spectra is in the UV-A range (300-360 nm). [Pg.1160]

PUVA therapy consists of the patient receiving total body irradiation with ultraviolet A (UVA) light several times a week after taking a psoralen. Most commonly available psoralens for photochemotherapy include 8-methoxypsoralen or 8-MOP (also called methoxsalen or xanthotoxin), 5-methoxypsoralen or 5-MOP (or bergapten), angelicin, 4,5 -dimethylangelicin, and 4,5, 8-trimethoxypsoralen or 4,5, 8-trimethoxypsoralen (TMP) [104]. Psoralen is taken 2 h before irradiation and can be administered orally (5-MOP or 8-MOP) or topically, either painted onto the skin surface or, more frequently, using a bath delivery system... [Pg.172]

See other pages where Xanthotoxin 8-methoxypsoralen is mentioned: [Pg.492]    [Pg.28]    [Pg.1063]    [Pg.812]    [Pg.286]    [Pg.1289]    [Pg.378]    [Pg.877]    [Pg.492]    [Pg.28]    [Pg.360]    [Pg.495]    [Pg.120]    [Pg.3088]    [Pg.286]    [Pg.160]    [Pg.708]    [Pg.120]    [Pg.181]    [Pg.906]    [Pg.181]    [Pg.863]    [Pg.204]    [Pg.1063]    [Pg.1072]    [Pg.812]    [Pg.32]    [Pg.92]    [Pg.156]    [Pg.165]    [Pg.190]   


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5-methoxypsoralene

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