X-Ray Molecular Structure of Genuine MYKO

When MYKO 63 is crystallized from saturated solutions in m-xylene, carbon disulfide or water, the single crystals so obtained belong to various space groups but the molecular geometry of the drug by itself appears strictly identical in the three cases (Fig. 15). Incidentally, these crystals do not contain in their unit cell 

As expected, the N3P3 ring is found to be perfectly planar. On the other hand, exocyclic nitrogen atoms have a highly pyramidal character, in contrast with the 

2 X-Ray Molecular Structure of MYKO 63 from its Benzene and CCl Clathrates 

The comparison of the three different MYKO 63 molecular structures so obtained calls for the following remarks. 

X-Ray investigations of MYKO 63 molecular structures make a remarkable flexibility of its aziridino wings conspicuous. Having in mind that these wings may generate the suitable carbocations for dialkylating DNA, we may assume that MYKO 63, owing to its versatile character, will have the capability of easily 

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