Worked cell culture reactor design example

15 WORKED CELL CULTURE REACTOR DESIGN EXAMPLE 

1 Conventional Batch Stirred Reactor with Air Sparging for Microcarrier-Supported Cells A Simple Design Methodology for Discerning the Rate-Controlling Step 

Duty It is required to design a stirred reactor using microcarrier-supported animal cells. The working capacity of the reactor (volume of broth) is 20 m The dispersion height to diameter ratio = 1. Disengagement volume equivalent to 1/3 of the total volume is to be provided above the broth level. Therefore, total reactor volume is 30 m and vessel diameter is 3 m. Impeller to be used is six-blade upflow pitched turbine with DIT = CIT = 0.33. 

Reactor Configuration Reactor diameter = 3 m. Impeller diameter (D/T = CIT= 0.33) is 1 m. 

Impeller to be used is six-blade upflow pitched turbine (6 PTU). 

---

B.15 WORKED CELL CULTURE REACTOR DESIGN EXAMPLE... 

---