With additional coordinating groups Oxime

An additional example of a functional group undergoing reaction at the alpha atom is provided by the reactions of coordinated oximes. The earliest observation on this class of system appears to have been reported by Barker who reacted bis (dimethylglyoxime) nickel with methyl iodide and dimethyl sulfate (3). The formulations suggested for the products are archaic however, the experiments have been repeated and found to be substantially correct (31). The reactions are exemplified in Equation 47. 

The interactions of compounds containing the oxime group with coordinated organonitriles are very important in template syntheses [384,413-416], These reactions take place as a nucleophilic addition and lead to the formation of complexes with unusual iminoacyl ligands. The iminoacylation reaction was studied in detail for various oximes and organonitriles, coordinated to PtCl4 [384,413-416]. Thus, the template transformation (3.192) of the discussed type in case of the oximes 744 takes place in acetonitrile or chloroform and yields complexes of the type 745 [413a] ... 

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