Willgerodt reaction, review

Molecular sieve Wavelength specificity s. Light, monochromatic Wilkinson rhodium catalyst s. Chlorotris(triphenyl-phosphine)rhodium(I) Willgerodt reaction, review 2,180s31... 

The Willgerodt reaction allows amide synthesis from aromatic aldehydes or ketones, using a secondary amine and a thiating agent. The mechanism of the more convenient Kindler modification, employing sulfur and morpholine, has been reviewed.281... 

Willgerodt reaction (1,705-706 1120-1121). This reaction and the Kindler modification have been reviewed in depth (172 references). ... 

Many other nitrogen- and sulfur-containing rings are available from reactions of the Willgerodt-Kindler type. Benzo- and pyridino-fused thia-zoles, for example, are formed from anilines (benzeneamines) and amino-pyridines, respectively.25 Asinger26 has reviewed the scope of these reactions in heterocyclic synthesis. 

Purrello, G. Some aspects of the Willgerodt-Kindler reaction and connected reactions. Heterocycles 2005, 65, 411-449. (Review). 

A review of the Willgerodt-Kindler reaction covering the literature through 1972 is available. Using DMF as solvent, the reaction has been applied to benzylamines and benzyl chlorides, giving TVTV-dimethylthiobenzamides the yields have been found to be different in the absence and presence of DMF. In the absence of DMF, the reaction shown in equation (5) was observed. ... 

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