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When is a D-optimal design appropriate

There are situations when a D-optimal design is the preferred choice  [Pg.183]

The available domain is truncated by constraints. A two-level design of any kind would necessitate the shrinking of the explored domain to accomodate the constraints. This would leave interesting parts of the domain uncovered by the design. A D-optimal design would select experiments to cover the whole domain of interest. [Pg.183]

Selection of complementary experiments to improve a model. When a series of experiments has been run to establish an initial model it is sometimes found that the model shows a lack of fit. If the experimenter can give a reasonable explanation for this, and he/she wishes to improve the model by adding some corrective terms, a D-optimal design can be used to select those complementary experiments which should be run to obtain maximum precision estimates of the parameters of the corrected model. [Pg.184]

It should be remembered that factorial, fractional factorial and Plackett-Burman designs are D-optimal designs. These designs can easily be constructed by hand. In [Pg.184]

A review on D-optimal regression designs has been given by St John and Draper.[5] [Pg.185]


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