Weight loss NIDDM

Let us dwell on the topic of obesity and weight loss for a bit longer. The American Diabetes Association has recommended that adults with NIDDM exercise for at least 20 min/day at 50% of the maximal O2 consumption rate (Ruderman and Schneider, 1992). This recommendation was designed to promote weight loss, since about 85% of people with NIDDM are also obese. However, evidence also suggests that exercise alone, even without weight loss, can improve the body s sensitivity to insulin. 

Nitrosamlnes, ascorbic acid and, 915-916 N-1 Inked glyCOptOtKins, 59 NMDA tcceplor, 252 n minus nomenclature, fatty acids, 640 Non-lnsuiln-dependent diabetes mellitus (NIDDM), 171,173-174 obesity as risk factor, 380 weight loss and, 389-391 Nonpolar solvent, defined. 26 Nonspecific nitrogen, 460 Noiepinepbrlne, 185,623 NO synthase, 200 NPU, see Not protein utilization... 

The clinical symptoms of hypcrglycaemia include polyuria, polydipsia, lassitude, weight loss, pruritus vulvae and balanitis. These symptoms are common to both NIDDM and IDDM but arc more pronounced in IDDM. It is important to remember that patients with. NIDDM may be completely asymptomatic. 

NIDDM is more common in obese people, and especially those with abdominal rather than subcutaneous obesity (section 6.2.3). Significant weight loss can often restore normal glycaemic control without the need for any other treatment. The so-called metabolic syndrome (also known as syndrome X) is the simultaneous development of insulin resistance, hypertension and hypertriglyceridaemia, all associated with (abdominal) obesity. 

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