Vulgarol

Bicyclo[2,2,l]heptanes.—Vulgarole (202 R=Ac) has been isolated from Artemisia vulgaris and Ferula dshizakensis has yielded a new borneol ester, isotschimgin (cf. Vol. 3, p. 58)." ... 

According to recent investigations, the commercially available oils derive from Artemisia herba-alba Asso (Morocco). Their qualitative composition is similar to the oil of Artemisia vulgaris, greater deviations have been observed quantitatively [165]. Nano et al. [166] demonstrated varying compositions in essential oils of various plant samples from Piedmont. Vulgarol, a bomane derivative, was detected as a new constituent in some of the oils. Spathulenol and a-cadinol, two sesquiterpene alcohols, as well as davanone were found by fork and co-workers [167, 168, 169]. 

Bicyclo[2,2,l]heptanes.—Last year s Report incorrectly identifies vulgarole [Vol. 8, p. 49, line 21, formula (202 R = Ac) should be (208 R = Ac)]. A review of interest to this section concerns oxidation of bicyclic hydrocarbons using oxygen, hydroperoxides, peracids, and hydrogen peroxide. The full paper on nojigiku alcohol has appearedthe isolation of a new compound (132) has been referred to already. 

Contains 0.3-1% of a bitter principle called marrubiin (a diterpene lactone) several di-terpene alcohols (e.g., marrubiol, marrubenol, peregrinol, and vulgarol) small amounts of alkaloids (ca. 0.3% betonicine, its stereoisomer turicine, and ca. 0.2% choline) trace of a volatile oil containing monoterpenes (a-pinene, camphene, limonene, sabinene. 

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