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Voltage-gated calcium current

Other antiseizure drugs regulate a subset of voltage-gated calcium currents 634... [Pg.629]

Bleakman, D., Brorson, J.R., Miller, R.J. The effect of capsaicin on voltage-gated calcium currents and calcium signals in cultured dorsal root ganglion cells, Br. J. Pharmacol. 1990, 101, 423-431. [Pg.515]

Reichling, D. B. MacDermott, A. B. (1991). "Lanthamun actions on excitatory amino acidgated currents and voltage-gated calcium currents in rat dorsal horn neurons. J Physiol, 441, 199-218. [Pg.187]

Arikkath, J. and Campbell, K.P. (2003) Auxiliary subunits essential components of the voltage-gated calcium channel complex. Current Opinion in Neurobiology 13, 298-307. [Pg.278]

Cribbs LL, Lee JH, Yang J, Satin J, Zhang Y, Daud A, Barclay J, Williamson MP, Fox M, Rees M, Perez-Reyes E (1998) Cloning and characterization of alphalH from human heart, a member of the T-type Ca2+ channel gene family. Circ Res 83 103-9 Currie KP, Fox AP (1997) Comparison of N- and P/Q-type voltage-gated calcium channel current inhibition. J Neurosci 17 4570-9... [Pg.66]

Quignard, J.F., Frapier, J.M., Harricane, M.C., Albat, B., Nargeot, J., and Richard, S. (1997) Voltage-gated calcium channel currents in human coronary myocytes. Regulation by cyclic GMP and nitric oxide. Journal of Clinical Investigation, 99 185-... [Pg.195]

Figure 4. Whole-cell currents recorded from an axolotl vomeronasal receptor neuron in an epithelial slice. Currents were elicited by applying a series of voltage pulses, fiom -80 mV to +60 mV, in 10 mV increments. Vhoid = -80 mV. (A) Currents recorded in standard amphibian physiological saline, before any channel blockers were washed onto the slice. (B) Currents recorded 3 min after 10 pM tetrodotoxin (TTX) was washed onto the cell. TTX blocks voltage-gated sodium currents, revealing a second inward current. (C) Currents recorded 9 min after a solution containing both 10 pM TTX and 1 mM CoCk was washed onto the slice. Cobalt blocks calcium currents, demonstrating that the rapidly-inactivating inward current shown in panel B was carried by calcium. Figure 4. Whole-cell currents recorded from an axolotl vomeronasal receptor neuron in an epithelial slice. Currents were elicited by applying a series of voltage pulses, fiom -80 mV to +60 mV, in 10 mV increments. Vhoid = -80 mV. (A) Currents recorded in standard amphibian physiological saline, before any channel blockers were washed onto the slice. (B) Currents recorded 3 min after 10 pM tetrodotoxin (TTX) was washed onto the cell. TTX blocks voltage-gated sodium currents, revealing a second inward current. (C) Currents recorded 9 min after a solution containing both 10 pM TTX and 1 mM CoCk was washed onto the slice. Cobalt blocks calcium currents, demonstrating that the rapidly-inactivating inward current shown in panel B was carried by calcium.
Voltage-gated calcium channels mediate calcium influx that controls many functions such as contraction, secretion, neurotransmission, and gene expression in different cell types. In neurons and neuroblastoma cells, menthol inhibits calcium currents measured from low voltage-activated (LVA) and high voltage-activated (HVA) calcium channels in the concentration range of 0.1-1 mM [38, 39]. Additionally, menthol also accelerates inactivation phase of the calcium current from HVA calcium channels in a concentration-dependent manner and without major calcium influence [39, 40]. [Pg.3996]


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See also in sourсe #XX -- [ Pg.275 ]




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Calcium currents

Current-voltage

Gate current

Gate voltage

Gating current

Voltage-gated

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