Vitamin for growth

CAS 150-13-0. NH2C6H4C02H. Required by many organisms as a vitamin for growth, active in neutralizing the antibacteriostatic effect of some sulfonamide drugs. 

Synthesis of the coenzymes and cosubstrates which are necessary in catalytic amounts in all fields of metabolism (Table 62) is restricted within the kingdom of living beings. Humans and animals, for instance, are unable to build most of these compounds. They have to take up these products (or close precursors) as so-called vitamins with the nutrients. Also most types of plant cells cultivated in vitro and some microbial strains need supplementation with certain vitamins for growth or optimation of cell division. Thiamine for instance is produced only in the leaves in higher plants and from these organs is transported to other tissues. Hence it is not formed in cultivated plant cells which have another state of cell specialization than the leaf tissues. 

All the strains tested require vitamins for growth, i.e. pantothenic acid and biotin (Delwiche, 1949), some of them need thiamine and / -amino-benzoic acid as well. The growth of all strains is stimulated by Tween 80 (Johnson and Cummins, 1972). Skerman (1967) included also the ability to utilize lactate as a taxonomic character. 

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