Virus-host systems Subject

The CHO ceU was chosen as the rAHF-PFM host ceU expression system for several reasons, as previously described. Among these reasons are the CHO cell line s documented resistance to infection by many human viruses and its ability to grow in a plasma- and albumin-free culture [24]. Following adaptation to a protein-free medium, the cell line was subjected to extensive testing for both known and unknown adventitious viruses [8]. 

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