Vinegar-like side chains

Effect of Changing the State of Vinegar-like Side Chains... 

Determination of AG ha for a Change in Functional State of Naturally Occurring Vinegar-like Side Chain... 

The vinegar-like side chains can exist in either of two different states, for example, the car-boxyl/carboxylate, COOH/COO, chemical couple and the amino/ammonium, -NH2/NH3, chemical couple. As demonstrated below, the uncharged state of the couple favors association of oil-like domains, whereas the charged state of the couple disrupts association of oillike domains by having destroyed the special hydration of oil-like groups in the process of achieving its own hydration. 

Oil and Vinegar Don t Mix, But, When Oil-like and Vinegar-like Side Chains of Proteins Are Forced to Coexist by Virtue of Structure (Primary,... 

Figure 2.1. The phase transition of oil-like groups separating from water produces motion. A A protein is described as a polypeptide chain molecule with different side chains, R-groups. B The side chains delineated simply as oil-like and vinegar-like (e.g., charged), are distributed along the chain. C The separation of oil-like groups from vinegar-like groups and the association of oil-like groups to form oil-like...

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