Vesicle electrokinetic chromatography,

Other electrokinetic chromatography techniques using liposomes (LEKC) and vesicles (VEKC) have also been applied for logP d estimation. Liposomes and vesicles are organized structures containing continuous bilayers of monomers enclosing an aqueous core region. 

Klotz, W. L., Schure, M. R., Eoley, J. P. Rapid estimation of octanol-water partition coefficients using synthesized vesicles in electrokinetic chromatography. J. Chromatogr. A 2002, 962, 207-219. 

Electrokinetic chromatography (EKC) using microemulsion is one of the most powerful tools for the rapid measurement of log P w with high reproducibility. Because it is relatively easy to manipulate the pseudostationary phases of EKC, a lot of phases have been reported for the measurement not only of physicochemical properties but also of the separation selectivity, such as polymer micelles (64) and double-chain surfactant vesicles (56-58,60,61). These phases are also interesting in terms of the correlation to bioactivity. 

M Hong, BS Weekley, SJ Grieb, JP Foley. Electrokinetic chromatography using thermodynamically stable vesicles and mixed micelles formed from oppositely charged surfactants. Anal. Chem. 70 1394-1403 (1998). 

AA Agbodjan, H Bui, MG Khaledi. Study of solute partitioning in biomem-brane-mimetic pseudophases by electrokinetic chromatography dihexadecyl phosphate small unilamellar vesicles. Langmuir 17 2893-2899 (2001). 

S. Terabe, Micellar electrokinetic chromatography, in Capillary Electrophoresis Technology (N. A. Guzman, ed.), Marcel Dekker, Inc., New York, 1993, pp. 65-87. J. N. Israelchvilli, in Physics of Amphiphiles Micelles, Vesicles and Microemulsions (V. Degiorgio and M. Corti, eds.). Proceedings of the International School of Physics Enrico Eermi, CourseXC, North-Holland, Amsterdam, 1985, pp. 24-37. 

Enormous advances and growth in the use of ordered media (that is, surfactant normal and reversed micelles, surfactant vesicles, and cyclodextrins) have occurred in the past decade, particularly in their chromatographic applications. New techniques developed in this field include micellar liquid chromatography, micellar-enhanced ultrafiltration, micellar electrokinetic capillary chromatography, and extraction of bioproducts with reversed micelles techniques previously developed include cyclodextrins as stationary and mobile-phase components in chromatography. The symposium upon which this book was based was the first major symposium devoted to this topic and was organized to present the current state of the art in this rapidly expanding field. 

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