Ventricular tachycardia thioridazine

Connolly MJ, Evemy KL, Snow MH. Torsade de pointes ventricular tachycardia in association with thioridazine therapy report of two cases. New Trends Arrhythmias 1985 1 157. 

Wilens TE, Stem TA. Ventricular tachycardia associated with desipramine and thioridazine. 

A series of 8 patients is reported who developed cardiac complications following medication with a variety of psychotropic drugs, mainly phenothiazines and tricyclic antidepressants. Most of the patients showed arrhythmias, disorders of conduction, or both. Five of the patients, all of whom were receiving thioridazine, developed ventricular tachycardia or fibrillation. Many of the patients described showed no evidence of preexisting heart disease and 3 were below the age of 35, when the complications developed. In one female patient of 35 years ventricular tachycardia was fatal. 

The case is reported of a 54-year-old woman who developed ventricular tachycardia following the administration of thioridazine in total daily doses of 1300 mg. 

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