Ventricular arrhythmias caused

Actions Quinidine inhibits ectopic arrhythmias and ventricular arrhythmias caused by increased normal automaticity. Quinidine also prevents reentry arrhythmias by producing bidirectional block through decreasing membrane responsiveness and pro-... 

In addition, to its hypotensive effect, rilmenidine has additional beneficial effects. In the cardiovascular field, it was shown to powerfully prevent the occurrence of experimental ventricular arrhythmias. Mammoto et al. (1996) reported that rilmenidine prevented the halothane-adren-aline induced arrhythmias in dogs. Our group has shown that rilmenidine was able to prevent the occurrence of ventricular arrhythmias caused by bicuculline injected i.c. in anaesthetized rabbits. This effect of potential clinical relevance was observed when rilmenidine was injected either i.c. or intravenously (Roegel et al., 1996). It is notable that this anti-arrhythmic action was observed at doses of rilmenidine too low to reduce blood pressure and that it was antagonized by idazoxan. Similar results were also obtained with moxonidine (Lepran and Papp, 1994 Mest et al., 1995). 

A. To control excessive sinus tachycardia or ventricular arrhythmias caused by catecholamine excess (eg, theophylline or caffeine), sympathomimetic drug intoxication (eg, amphetamines, pseudoephedrine, or cocaine), or excessive myocardial sensitivity (eg, chloral hydrate, freons, or chlorinated and other hydrocarbons). 

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