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Vectors phage integration

Persic L, Roberts A, Wilton J, Cattaneo A, Bradbury A, Hoogenboom H, An integrated vector system for the eukaryotic expression of antibodies or their fragments after selection from phage display libraries, Gene, 187 9-18, 1997. [Pg.468]

If the host cells are bacteria, commonly nsed vectors are bacteriophage (viruses that infect bacteria), plasmids (extrachromosomal pieces of circnlar DNA that are taken up by bacteria), or cosmids (plasmids that contain DNA seqnences from the lambda phage). When eukaryotic cells are used as the host, the vectors are often retroviruses, adenoviruses, free DNA, or DNA coated with a lipid layer (liposomes). The foreign DNA sometimes integrates into the host cell genome or it exists as eip-somes (extrachromosomal fragments of DNA) (See section III.D. of this chapter.)... [Pg.303]

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