Variable Functionalizations Around the Pentameric Periphery

Entry Reacting partners Molar ratio Yield (%t 

Mixing 17a and 17b in a 4 1 ratio produced two major spots, corresponding to pentamers 16a and 16m, containing five and four 17a units (Lane 3, Fig. 9.16), respectively. Similarly, mixing 17a and 17b in 1 4 ratio produced another two 

In conclusion, it was established here that the POCla-mediated one-pot macrocyclization proceeds predominantly by a chain-growth mechanism whereby the 

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