Valeriana wallichii for

Wasowski C, Marder M, Viola H, Medina JH, Paladini AC. Isolation and identification of 6-methylapigenin, a competitive ligand for the brain GABAa receptors, from Valeriana wallichii. Planta Med 2002 68 934-936. 

The rhizomes and roots of Valeriana wallichii DC. contain 6-methylapigenin, which is a competitive ligand for GABAa receptor (38). In the Asia-Pacific region, Nar-dostachys chinensis L., Nardostachys jatamansis DC., Patrinia scabiosaefolia Link, Valeriana officinalis L., Valeriana dageletiana Nak. ex Maekawa, and Valeriana hardwickii Wall, are used as alternative remedies. 

C,5H24,Mr204.36,oil,bp. 120-I30 C(133 Pa), [aJo +35.8° (CHClj). Sesquiterpene from Aspergillus migatus and Valeriana wallichii, occurs in nature only in the trans form. Biosynthesis from famesyl pyrophosphate /S-B. is the biosynthetic precursor of the antibiotics ovalicin and fumagillin. For synthesis, see Lit. absolute configuration, seeUt. ... 

Valerian consists of the dried rhizome and roots of Valeriana officinalis (Valerianaceae). Valeriana wallichii and V. edulis also serve as commercial sources of the drug. Species from related genera also are known to contain the active principles. Valerian has been used as a calmative in nervousness and hysteria for at least 1000 years. A series of water-soluble glycosides, collectively called valepotriates, are responsible for the mild tranquilizing activity. These preparations are widely available in Europe (Charlwood and Charlwood, 1991 Tyler et al., 1981). 

Among the tricyclic aromadendrols viridiflorol (202), which occurs, for instance, in peppermint oil from Piedmont Mentha piperita L. Italo-Mitcham), is supposed to confer to this essential oil its characteristic note. When added to normal peppermint oils, (202) enhances their sweetish scent without modifying their taste and aroma 415). A dia-stereoisomer of (202), globulol, is present in eucalyptus oil, and is described as odorless 204). Maaliol (203), an alcohol which was first isolated from maali resin 62), was found in fresh roots of Valeriana officinalis L. (595) and also in the Indian variety Valeriana Wallichii D.C. 416). Maaliol-containing oils from Valeriana Wallichii D.C. are said to have a finer odor 582). In addition, maalioxide (204) 62) was found in the same oil 416 presumably as an artifact of alcohol (203). The cyclic ether is characterized by its fine woody odor quality 443). 

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