V- phenylsulfonyl benzenesulfonamide

Alternative Names A-fluorobenzenesulfonimide iV-fluorobis-(phenylsulfonyl)amine A-fluorodibenzenesulfonimide, NFSi. [Pg.319]

Form Supplied in white or slightly yellow solid, 98% purity commercially available. [Pg.319]

Purification flash chromatography (Si02, CH2CI2) and/or crystallization from Et20. [Pg.319]

Handling, Storage, and Precautions handle and store at rt or below protected from light, preferably under nitrogen or argon. Thermally stable up to 180 °C decomposes exothermally at higher temperatures. Reacts with easily oxidized compounds such as iodide. This reagent should he handled in a fume hood. [Pg.319]

Fluorination of Enolates and Silyl Enol Ethers. iV-fluoro-Af-(phenylsulfonyl)henzenesulfonamide (1) can be used successfully to prepare a-fluorocarbonyl compounds starting from esters, ketones, or 8-dicarbonyl precursors by electrophilic fluorination of the corresponding enolates (eqs 1-3) or silyl enol ethers (eq 4). Diastereoselective fluorination of enolates with 1 has recently been reported. [Pg.319]

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