Uvaria zeylanica

Another series of compounds that appear to be derived from ijo-chorismic acid are cyclohexene oxides such as cro-tepoxide (36), senepoxide (37), and pipoxide (38) from Croton macrostachys (Euphorbiacee), Uvaria zeylanica (An-nonaceae), and Piper hookeri (Piperaceae), respectively (Fig. 7.13). These compounds have demonstrated antitumor activity (Jolad et al., 1981). 

Jolad S D, Hoffmann J J, Schram K H, Cole J R, Tempesta M S, Bates R B 1981 Structures of zeylenol and zeylena, constituents of Uvaria zeylanica (Annonaceae). J Org Chem 46 4267-4272... 

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