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UV-associated skin carcinogenesis

Data from animals and humans indicate that at least some photoirritants enhance UV-associated skin carcinogenesis. 8-Methoxypsoralen (8-MOP), used in psoralen plus UVA treatment therapy,12 is considered to be a photococarcinogen in humans, whereas several fluoroquinolones have been demonstrated to be photoirritants and photochemical carcinogens in hairless mice.11 However, data for many other classes of pharmaceuticals are unavailable. [Pg.80]

IV. TESTING FOR ENHANCEMENT OF UV-ASSOCIATED SKIN CARCINOGENESIS (DIRECT PHOTOCHEMICAL CARCINOGENICITY OR INDIRECT EFFECTS IN SKIN)... [Pg.82]


See other pages where UV-associated skin carcinogenesis is mentioned: [Pg.354]    [Pg.79]    [Pg.79]    [Pg.86]    [Pg.354]    [Pg.79]    [Pg.79]    [Pg.86]    [Pg.83]    [Pg.1429]    [Pg.1429]    [Pg.117]    [Pg.3628]    [Pg.935]    [Pg.936]    [Pg.187]   


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Carcinogenesis

Skin Carcinogenesis

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