Urine glucose isolation from

D-Acosamine (2,3,6-dideoxy-3-amino-D-otraZ>mo-hexose) has been isolated from hydrolysis of the antibiotic sporoviridin/ which contains at least two acosamine moieties in addition to viosamine (4-amino-4,6-dideoxy-D-glucose). 2-Acet-amido-glucal has been isolated from the urine of patients with sialuria and 1,5-dideoxy-l,5-imino-D-mannitol is present in the legumes Lonchocarpus sericens. ... 

Recently, we have isolated the urea derivative of glucose, V-carbamoyl-P-D-glucopyranosylamine (glucose ureide), from human urine. We hypothesise that carbonyls react with urea in vivo to form urea derivatives, including ureides, which are then excreted as urinary constituents. In this experiment, we have developed a systematic approach for detection of urinary carbonyls in order to verify the in vivo modification of carbonyls with urea. 

Positive ESI mass spectrum (la) (C7Hj406N2 222) and IH-NMR spectrum (lb) of glucose ureide isolated from human urine. 

The isolation of kallikrein (mol. wt. 3.2 x 10 ), a protease that releases kinin from kininogen, from rat urine has been reported. Kallikrein contains five residues of 2-amino-2-deoxy-D-glucose per molecule. Excessive amounts of oligosaccharides rich in sialic acid have been detected in the urine of patients with I-cell disease or mucolipidosis, indicating that there is a deficiency of a-neuraminidase in these diseases. ... 

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