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Urinary Thromboxane

Zipser, R.D., Radvan, G.H., Kronborg, I.J., Dnke, R., Little, T.E. Urinary thromboxane B2 and prostaglandin E2 in the hepatorenal syndrome evidence for increased vasoconstrictor and decreased vasodilator factors. Gastroenterology 1983 84 697-703... [Pg.331]

Urinary thromboxane is the end metabolite of thromboxane A2, which is a measure of platelet aggregation. Urinary levels are elevated in patients with unstable coronary disease in keeping with the known participation of platelets in the pathogenesis of CAD. It is difficult to measure, and collecting urine in acute situation is at times problematic. [Pg.1635]

Kawaguchi A, Goldman MEI, Shapiro R, Foegh ML, Ramwell PW, Lower R.D. Increase in urinary thromboxane B2 in rats caused by cyclosporine. Transplantation 1985 40 214-216. [Pg.439]

Uyama O, Nagatsuka K, Nakabayashi S, Isaka Y, Yoneda S, et al. 1985. The effect of a thromboxane synthetase inhibitor, OKY-046, on urinary excretion of immunoreactive thromboxane B2 and 6-keto-prostaglandin El alpha in patients with ischemic cerebrovascular disease. Stroke 16 241-244. [Pg.90]

Laivouri H, Horatta O, Viinikka L, Ylikorkala O. Dietary supplementation with primrose oil or fish oil does not change urinary excretion of prostacyclin and thromboxane metabolites in pre-eclamptic women. Prostaglandins Leukot Essent Fatty Acids 1993 49 619-694. [Pg.230]

Benigni A, Chiabrando C, Piccinelli A, Perico N, Gavinelli M, Furci L, Patino O, Abbate M, Bertani T, Remuzzi G. Increased urinary excretion of thromboxane B2 and 2, 3-dinor-TxB2 in cyclosporin A nephrotoxicity. Kidney Int 1988 34 164-174. [Pg.439]

Burch, R.M. and Halushka, P.V. (1980). Thromboxane and stable prostaglandin endo-peroxide analogs stimulate water permeability in the toad urinary bladder. ]. Clin. Invest., 66, 1251-57... [Pg.54]

Figure 6.5 Percent change in thromboxane A2 and prostacyclin biosynthesis, measured as excretion of their urinary metabolites, 2,3-dinor-thromboxane (Tx) 82 and 2,3-dinor-6-keto-prostaglandin (PG) respectively, in response to a thromboxane A2/prostaglandin endoperoxide receptor antagonist (L636,499) alone and in combination with a thromboxane synthase inhibitor (U63,557A) in the chronic canine model of coronary thrombosis. (Note that occlusion did not occur in dogs treated with the combination therapy)... Figure 6.5 Percent change in thromboxane A2 and prostacyclin biosynthesis, measured as excretion of their urinary metabolites, 2,3-dinor-thromboxane (Tx) 82 and 2,3-dinor-6-keto-prostaglandin (PG) respectively, in response to a thromboxane A2/prostaglandin endoperoxide receptor antagonist (L636,499) alone and in combination with a thromboxane synthase inhibitor (U63,557A) in the chronic canine model of coronary thrombosis. (Note that occlusion did not occur in dogs treated with the combination therapy)...
Figure 6.6 Urinary 2,3-dinor-thromboxane (Tx) B2 and 2,3-dinor-6-keto-prostaglandin (PG) and plasma II-dehydro-TxB2 (inset) before and following exercise-induced myocardial ischaemia in patients with stable coronary artery disease... Figure 6.6 Urinary 2,3-dinor-thromboxane (Tx) B2 and 2,3-dinor-6-keto-prostaglandin (PG) and plasma II-dehydro-TxB2 (inset) before and following exercise-induced myocardial ischaemia in patients with stable coronary artery disease...
Figure 6.7 Urinary 2,3-dinor-thromboxane (Tx) (O—O) and 2,3-dinor-6-keto-prosta-... Figure 6.7 Urinary 2,3-dinor-thromboxane (Tx) (O—O) and 2,3-dinor-6-keto-prosta-...

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