Urea herbicides neburon

SE Katz. Determination of the substituted urea herbicides linuron, monuron, diuron, neburon and fenuron in surface waters. J Assoc Off Anal Chem 49 452-456, 1966. 

Herbicides Substituted urea herbicides Diuron, neburon, phenobenzuron and isoproturon Adsorption LiChrosorb SI 60 Water saturated with dichloromethane (the role of water being to block the most active silanol sites thereby... 

By varying the aryl substituent and the 1-substituents of 3-aryl ureas several effective herbicides have been prepared, such as neburon, l-butyl-3-(3,4-dichlorophenyl)-l-ntethylurea (27) trimeturon, 3-(4-chlorophenyl)-0,l,l-trimethylisourea (28) buturon, 3-(4-chlorophenyl)-l-methyl-1-(1-methylprop-2-ynyl)urea (29) and Proban , 3-(3,4-dichlorophenyl)-l-isopropyl-l-(2-propynyl)-urea (30). Hiose containing unsaturated side-chains include siduron, l-(2-niethyicyclohexyl)-3-phenylurea (31), and methazole, 2-(3,4-dichlorophenyI)-4-methyl-1,2,4-oxa azolidine-2,S-dione (32). 

The retention characteristics of nine phenylureas (e.g., phenuron, hydroxy-methoxuron, bis-A, A -(3-chloro-4-methylphenyl)urea, neburon, and 7V-phenylurea) were studied on a cyanopropyl column (A = 254 nm) under normal-phase conditions of hexane/IPA (90/10 to 10/90), and reversed-phase conditions of IPA/water (10/90 to 90/10). Complete resolution of all nine herbicides was not achieved, but six were well resolved and eluted within 15 min using an isocratic 90/10 hexane/IPA mobile phase [210]. Extensive tables of k values for a wide range of isocratic mobile phases for both the NP and RP separations were presented. 

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