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Ultrasound-assisted formation of a solid phase sonocrystallization and sonoprecipitation

Ultrasound-assisted formation of a solid phase sonocrystallization and sonoprecipitation [Pg.47]

Sonocrystallization is the currently accepted name for the use of power ultrasound to control and accelerate the course of a crystallization process. This effect had previously been used in the salting-out process for years, and has been found to have a favourable [Pg.47]

Like crystallization, US also successfully assists the formation of extremely finely divided and uniform particles, which can be termed sonoprecipitation. This effect, which has not yet been used in analytical chemistry and might facilitate sample preparation in nephelometric or turbidimetric methods, has been widely exploited by the pharmaceutical industry to prepare liquid dispersions of drugs for oral or subcutaneous administration where extremely small particle sizes ensure stable suspensions of the drug and faster assimilation into the body. On a laboratory scale, US-assisted precipitation of magnesium carbonate in a model system has been studied [65]. [Pg.48]




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Phase formation

Solid formation

Solid phase formation

Sonocrystallization

Sonocrystallization ultrasound

Sonoprecipitation

Ultrasound formation

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