Ulcer, pantothenic acid vitamin

A deficiency purely m pantothenic acid has probably never occurred, except Ln controlled studies. Persons suffering from severe malnutrition would be expected to be deficient in the vitamin. Studies with animals have shown that consumption of a diet deficient in the vitamin results in a loss of appetite, slow growth, skin lesions, ulceration of the intestines, weakness, and eventually death. Pantothenic acid deficiency also results in the production of gray fur in animals whose fur is colored. Biochemical studies with deficient animals have revealed severe de-creasesinpantothenicacidlevelsina variety of tissues, bu I only m (xlera le declines in the levels of coenzyme A in liver and kidney and maintenance of coenzyme A levels Ln the brain Smith t ai, 1987), Some striking defects in glycogen and ketone bc dy metabolism have been noted in pantothenic acid-deficient animals. 

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