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Tumorigenesis, oncogenes and

Malfunction of Signaling Pathways and Tumorigenesis Oncogenes and Tumor Suppressor Genes... [Pg.469]

As mentioned earlier, epidemiological studies have revealed that the incidence of cancer increases exponentially with age. From these studies, it has been suggested that three to seven mutations or hits are necessary for cancer development. Definitive proof that these hits occur in oncogenes and tumor suppressor genes and that these genes cooperate in tumorigenesis comes from molecular studies in human cancer and mouse cancer models. [Pg.584]

Dodelet, V. C., and Pasquale, E. B. (2000). Eph receptors and ephrin ligands Embryo-genesis to tumorigenesis. Oncogene 19, 5614—5619. [Pg.100]

Bouck, N. (1992) Angiogenesis A mechanism by which oncogenes and tumor suppressor genes regulate tumorigenesis. Cancer Treat. Res. 63,359-371. [Pg.184]

See other pages where Tumorigenesis, oncogenes and is mentioned: [Pg.309]    [Pg.124]    [Pg.293]    [Pg.248]    [Pg.261]    [Pg.557]    [Pg.584]    [Pg.309]    [Pg.165]    [Pg.621]    [Pg.243]    [Pg.67]    [Pg.457]    [Pg.332]    [Pg.327]    [Pg.127]    [Pg.243]    [Pg.266]    [Pg.1342]    [Pg.475]    [Pg.448]    [Pg.4]    [Pg.32]   
See also in sourсe #XX -- [ Pg.200 , Pg.210 , Pg.230 ]



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