Tubocurarine Theophylline

Tubocurarine Chloride Tyramine Hydrochloride Theophylline Hydroflumethiazide Azacyclonol Hydrochloride Nitrofurantoin Theophylline Hydrate Ethisterone... 

Furosemide (40-80 mg) has been reported to enhance and prolong D-tubocurarine-induced block in anephric patients (63). In animals low doses potentiated D-tubocur-arine (and suxamethonium) probably via presynaptic effects, while high doses (1-40 mg/kg in cats) reversed the neuromuscular actions of these relaxants (64). The effects of high doses were similar to those of theophylline. 

A study in rabbits showed that, at therapeutic concentrations of theophylline, the effects of tubocurarine were increased, but there do not appear to have been any studies done in humans. 

Fuke N, Martyn J, Kim C, Basta S, Concentration-dependent interaction of theophylline with c -tubocurarine. JAppl Physiol (1987) 62, 1970-4,... 

Many of the most important therapeutic agents for man are alkaloids among these are atropine, berberine, caffeine, cocaine, codeine, colchicine, emetine, ephedrine, ergota-mine, hyoscyamine, morphine, physostigmine, pilocarpine, quinidine, quinine, reserpene, scopolamine, strychnine, theophylline, tubocurarine, and yohimbine. 

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