Tuberomammillary nucleus afferents

The histamine neurons in the tuberomammillary nucleus, in the posterior hypothalamus, project to the cortex and thalamus and receive an afferent input from... 

Ericson, H., Blomqvist, A. Kohler, C. (1989). Brainstem afferents to the tuberomammillary nucleus in the rat brain with special reference to monoaminergic innervation. J. Comp. Neurol 281, 169-92. 

Yang, Q. Z. Hatton, G. I. (1997). Electrophysiology of excitatory and inhibitory afferents to rat histaminergic tuberomammillary nucleus neurons from hypothalamic and forebrain sites. Brain Res. 773, 162-72. 

The importance of peptide transmitters in the modulation of sleep and wakefulness has become apparent in recent years. Previous work had focused on the role of monoamines in the circuitry that regulates the transitions between states of vigilance. Histaminergic neurons in the tuberomammillary nucleus are known to be key players in the activation of subcortical afferents during wakefulness (Wada et al, 1991). Activity of noradrenergic neurons in the locus coeruleus correlates with the state of vigilance (Jones, 1991). The role of serotonergic neurons in rapid eye movement (REM) sleep has also been established (Lydic et al., 1987 Monti Jantos, 1992 Fabre et al., 2000). 

---

See also in sourсe #XX -- [ ]

---