TRNAVAL-Ribozyme Expression of the Gene for CBP

The effects of tRNAVal-ribozymes on the specific target mRNA, namely, the transcript of the CBP gene, were examined by measuring the level of CBP itself in F9 cells that had been transfected with the plasmids that encoded the various tRNAVal-ribozymes. [Pg.409]

A ROLE FOR THE TRANSCRIPTIONAL COACTIVATOR CBP DURING THE RA-INDUCED DIFFERENTIATION OF F9 CELLS [Pg.410]

Our tRNA -ribozymes, targeted to CBP mRNA, had high activity, which allows us to investigate the function of the transcriptional co-activator CBP in F9 cells. [Pg.410]

Treatment of F9 eells with RA decreases the rate of proliferation of F9 [Pg.414]

Guerrier-Takada, C., Gardiner, K., Marsh, T., Pace, N. and Altaian, S. 1983, Cell 35 849-857. [Pg.417]

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