Triose phosphate dehydrogenase inhibition

Heavy metals frequently act as enzyme inhibitors particularly when free -SH groups participate in the reaction. Papain, urease, myosin, triose phosphate dehydrogenase and many other enzymes fall into this category and are readily inactivated by Ca, Hg " " etc. The inhibition may sometimes be overcome by removing the metal ion, e.g. with H2S or with a chelating agent such as EDTA. 

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