Trimethyl decalone synthesis

Shing, T. K. M., Lee, C. M., Lo, H. Y. Synthesis of the CD ring in taxol from (S)-(+)-carvone. Tetrahedron Lett. 2001,42, 8361-8363. Marchand, A. P., Kumar, V. S., Hariprakasha, H. K. Synthesis of novel cage oxaheterocycles. J. Org. Chem. 2001,66, 2072-2077. Demnitz, F. W. J., Philippini, C., Raphael, R. A. Unexpected Rearrangement in the Peroxytrifluoroacetic Acid-Mediated Baeyer-Villiger Oxidation of trans-3p-Hydroxy-4,4,10p-trimethyl-9-decalone Forming a 7-Oxabicyclo[2.2.1]heptane. Structure Proof and Total Synthesis of ( )-Farnesiferol-C. J. Org. Chem. 1995, 60, 5114-5120. 

Let us now discuss some applications of microemulsions in catalytic processes. It has been shown in [298] that the use of microemulsions instead of organic solvents for electrochemical reactions is advantageous from both economical and ecological reasons. The electrode/fluid interface in microemulsions probably consists of a dynamic layer of surfactant molecules packed more loosely on the electrode than in aqueous solutions. Microemulsions provide good yields of carbon-carbon addition products in reactions catalysed by cobalt complexes when preparing vitamin B 2. Excellent stereo-selective control in microemulsions made with the cationic surfactant cetyl trimethyl ammonium bromide was demonstrated for the catalytic cyclisation of 2-(4-bromobutyl)-2-cycIohexene-l-one to 1-decalone. Electrochemical synthesis may be a viable future approach to environmentally friendly chemical methods. 

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