Triiodothyronine tablets

Sample preparation Grind a tablet, add 50 jxg 3,3, 5 -triiodothyronine, add 20 mL solvent A, stir for 10 min, add 40 mL solvent B, stir for 30 min, filter. Remove the upper layer and wash it six times with 15 mL portions of water saturated with butanol, evaporate under vacuum at 40-42°, reconstitute in 2.5 mL 3% ammonium hydroxide in MeOH, inject an aliquot (Anal.Lett. 1979, 12, 1201). (Prepare the solvents by mixing 1.8 L 1-butanol,... 

Fish, L.H. Schwartz, H.L. Cavanaugh, J. Steffes, M.W. Bantle, J.R Oppenheimer, J.H. Replacement dose, metabolism, and bioavailability of levothsu-oxine in the treatment of hypothyroidism. Role of triiodothyronine in pituitary feedback in humans. N.Engl.J.Med., 1987, 316, 764-770 [tablets]... 

A. An acute ingestion of more than 5 mg of levothyroxine (T4) or 0.75 mg of triiodothyronine (T3) is considered potentially toxic. An adult has survived an ingestion of 48 g of unspecified thyroid tablets a 15-month-old child had moderate symptoms after ingesting 1.5 g of desiccated thyroid. 

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