Triglycerides exogenous, fatty acids

Figure 26-18 Exogenous lipoprotein metabolism pathway. TG, Triglyceride CE, cholesterol ester FC, free cholesterol Ft, phospholipids HDL, hIgh-density lipoproteins FA, fatty acid LPL, lipoprotein lipase 6, apolipoprotein B-48 A, apolipoprotein A-i C, apolipoprotein C-ll , apolipoprotein E. (From Rifai N. Lipoproteins and apolipoproteins Composition, metabolism, and association with coronary heart disease. Arch Pathol Lab Med 1986 10 694-701. Copyright 1986, American Medical Association.)...

In an exogenous pathway, dietary cholesterol and triglycerides are absorbed by the gut enterocytes in the form of free cholesterol, fatty acids, and monoacylglycer-ols. Subsequently, the cholesteryl esters and triglycerides are incorporated into the triglyceride-rich chylomicrons and these processes involve several of the apolipopro-teins. The chylomicrons pass into the intestinal lymph system and then into the vascular circulation via the thoracic duct. Lipoprotein lipase (LPL) enables the transfer of fatty acids and triglycerides to the cells. Chylomicron remnants are transported to hepatic receptor sites. 

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