Triglyceride population distributions

FHBL (OMIM 107730) is a codominant disorder characterized by plasma levels of total cholesterol, LDL-cholesterol, triglycerides, and apoB below the fifth percentile of the distribution in the general population. FHBL is genetically heterogeneous it may be linked to the apoB gene. The best-characterized FHBL cases are those due... 

Figure 16=3 Observed and hypothetical distributions of 500 triglycerides values in serum (in mmol/L). A, The vertical bars of the left histogram show the number of observations in the Interval divided by the total number of observations. The curve is the estimated probability distribution of the population, assuming random sampling and a log-Gaussian distribution.

It is characterised by moderately raised triglycerides, low high-density lipoprotein (HDL)-chole-sterol, and the accumulation of cholesterol-enriched remnant lipoprotein particles. Total and LDL-cholesterol concentrations mainly reflect those of the background population but there are important qualitative changes in LDL particle distribution. 

Schaefer, L. E. Serum cholesterol-triglyceride-distribution in a normal New York City population. Amer. J. Med. 36, 262 (1964). 

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