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Triggered drug delivery systems

This drug design is already pointing to an enzyme-triggered drug delivery system. [Pg.42]

Timko BP, Dvir T, Kohane DS (2010) Remotely triggerable drug delivery systems. Adv Mater 22 4925 943... [Pg.2933]

Heller, J., S.H. Pangburn and K.V. Roskos, Development of enzymratically degradable protective coatings for use in triggered drug delivery systems. II. Derivatized starch hydrogels, Biomaierials, 11 (1990)... [Pg.235]

Kotamraj, R, Russu, W. A., Jasti, B., Wu, J., Li, X. (2011). Novel integrin-taigeted binding-triggered drug delivery system for methotrexate. Pharmaceutical Research, 28(12), 3208-3219. [Pg.255]

Tumor-targeted drug delivery systems can be classified based on three major approaches (i) passive targeting (ii) active targeting (Fig. 1) and (iii) external stimuli triggering. The advantages and challenges of each approach are discussed below. [Pg.1326]

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Enzyme-triggered drug delivery system

Trigger System

Triggerable

Triggers

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