Tri f-butoxy silanethiol

Handling, Storage, and Precautions thiols are known to be susceptible to autooxidation. This reagent may be toxic and may possess an unpleasant order. It should be kept under an inert atmosphere and handled with care. 

Related Reagents. f-Butyldimethylchlorosilane f-Butyl-dimethylsilyl Trifluoromethanesulfonate Chlorotriethylsilane. 

Paul Sampson Kent State University, Kent, OH, USA 

Form Supplied colorless liquid, not commercially available. 

Analysis of Reagent Purity the reagent may be checked by bp or analyzed by NMR spectroscopy. 

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Thiol-catalyzed Radical-chain Cyclization of Unsaturated Acetals and Thioacetals. When the unsaturated dioxolane 1 and a radical initiator, 2,2-di(t-butylperoxy)butane (DBPB), were heated at 125 °C in octane in the presence of tri(f-butoxy) silanethiol (TBST), the spirocyclic ketal 2 was formed cleanly and isolated in 92% yield (eq 1). When the reaction was performed in the absence of TBST, compound 2 was not detected. TBST is... 

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