Transplacental transmission

Passive immunity Providing temporary protection from disease through the administration of exogenously produced antibody (i.e., transplacental transmission of antibodies to the fetus or the injection of immune globulin for specific preventive purposes). 

Untreated acute toxoplasmosis among pregnant women can lead to infection of the fetus via transplacental transmission (Varella et ah, 2009.). At first examination, newborns affected by congenital infection may seem normal however, serious sequelae, such as neurological impairment and blindness, can develop witiiin a few years lafer (Dunn et ah, 1999 Remington et ah, 2006 Safadi et ah, 2003.). 

American trypanosomiasis, or Chagas disease, is caused by Trypanosoma cruzi. It affects -20 million people from Mexico to South America, where the chronic form of the disease is a major cause of cardiomyopathy, megaesophagus, megacolon, and death. Bloodsucking triatomid bugs most commonly transmit this infection to young children transplacental transmission also may occur in endemic areas. 

Shinefield HR, Townsend TE. Transplacental transmission of western equine encephalomyelitis. J Ped. 1953 43 21-25. 

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