Transition metals template synthesis of rotaxanes

Blanco, M.-J., Transition-Metal-Templated Synthesis of Rotaxanes, 23, 125. 

This chapter will be concerned mainly with the transition-metal-templated synthesis of rotaxanes. General features of these compounds, including stereochemical issues, will be addressed at first. The intent, however, is not to... 

PART II TRANSITION METAL-TEMPLATED SYNTHESIS OF ROTAXANES... 

The precatenate intermediate can be regarded as a threaded complex, which is thermodynamically stabilized by coordination bonds, from this simple consideration, a transition metal-templated synthesis of rotaxanes was devised, the principle of which is shown in Figure 28 [117]. The threading step (i) is a complexation reaction. 

Figure 28 Schematic representation of the principle of transition-metal templated synthesis of rotaxanes from macrocyclic chelate (A), metal cation (black disk) and open chelate (B). The latter bears functions X at its extremities, which will be used for anchoring or constructing the stoppers (represented as diamonds), (i) Threading step (ii) stoppering step (iii) removal of the metal template.

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