Transition metal catalysts enantioselective fluorination

Improving Enantioselective Fluorination Reactions Chiral N-Fluoro Ammonium Salts and Transition Metal Catalysts... [Pg.201]

To summarise, the development of novel enantioselective fluorination methods with the aid of either chiral N-fluoro ammonium salts or transition metal catalysts has established truely practical routes towards chiral fluorinated compounds. Despite the current mechanistic uncertaincies it appears that a door has been opened for exciting and promising further development of asymmetric (catalytic) fluorination reactions in the near future [31, 32]. [Pg.208]

Muniz K (2003) Improving enantioselective fluorination reactions chiral N-fluoro ammonium salts and transition metal catalysts. In Schmalz HG, Wirth T (eds) Organic synthesis highlights. Wiley-VCH, Weinheim... [Pg.119]

Relatively soft, late transition-metal Lewis acids are also suitable catalysts for electrophilic fluorination. Indeed, the cationic chiral mthenium(II)-(15,25)-A,/V -bis(o-(diphenyl-phosphino)benzylidene)cyclohexane-1,2-diamine complex is a powerful catalyst for the enantioselective fluorination of (3-keto esters (Scheme 44.25). ... [Pg.1360]