Transition metal auto-oxidation reaction

Traces of transition metals accelerate also auto-oxidation reactions and the decomposition of LOOH to LOO, LO, and cytotoxic aldehydes [139]. Agents that complex these transition metals decrease their biological effects dramatically [36],... 

Mixed complex formation has been postulated in the oxidation of sulphite catalysed by transition-metal ions. Several reactions are observed in the presence of copper(ii). The auto-oxidation rate is catalysed with formation of the species [00(803)202] " as intermediate. In the presence of propan-2-ol (ROH), however, an inhibition reaction, dependent on [SOs ] and [ROH], is observed. Induced oxidation of the inhibitor by copper(n) is also a factor, the rate being a function of [Cu ]. In the latter system the complex [Cu(SO )-(R0H)02] is considered as the reactive species,... 

Scheme 2.9 Mechanism of an Auto-Oxidation Reaction Catalyzed with a Transition Metal.

Glucose may auto-oxidize (like other alphahydroxy-aldehydes) and generate hydroxyl radicals in a transition-metal-catalysed reaction, and induce both fragmentation and conformational changes in glycated proteins (Hunt et al., 1990). 

The use of transition-metal-substituted aluminophosphates (AIPOs) as catalysts for free-radical auto-oxidations of hydrocarbons, a type IIaRH reaction, has been explored by several groups [60-62]. In a series of elegant contributions, Thomas... 

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