Transgenic mouse models Parkinsonism

Sidhu, J. S., Rajawat, Y. S., Rami, T. G., Gollob, M. H., Wang, Z., Yuan, R., Marian, A. J., DeMayo, F. J., Weilbacher, D., Taffet, G. E., Davies, J. K., Carling, D., Khoury, D. S., and Roberts, R. 2005. Transgenic mouse model of ventricular preexcitation and atrioventricular reentrant tachycardia induced by an AMP-activated protein kinase loss-of-function mutation responsible for Wolff-Parkinson-White syndrome. Circulation 111 21-29. 

Masliah E, Rockenstein E, Veinbergs I, Sagara Y, Mallory M, Hashimoto M, Mucke L (2001) p-Amyloid peptides enhance a-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer s disease and Parkinson s disease. Proc Natl Acad Sci USA 98 12245-12250. 

Higashi S, Moore DJ, Colebrooke RE, Biskup S, Dawson VL, Arai H, Dawson TM, Emson PC (2007b) Expression and localization of Parkinson s disease-associated leucine-rich repeat kinase 2 in the mouse brain. J Neurochem 100 368-381 Higgins GA, Jacobsen H (2003) Transgenic mouse models of Alzheimer s disease phenotype and application. Behav Pharmacol 14 419—438... 

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