Transferred nuclear Overhauser effect trNOE

Meyer et al. recently reported transfer NOE (nuclear overhauser effect) (trNOE) (88), which detects the strong negative trNOE effect of receptor-bound molecules compared to the weak, positive trNOE of unbound compounds without the need of receptor labeling the method was used to identify an E-selectin antagonist from an artificially assembled 10-member library of saccharides (89). 

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