Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Transcription factors definition

The adaptive response to xenobiotics is orchestrated in the cell by a subset of receptors that act primarily in the nucleus. For this chapter, we will employ a liberal definition of nuclear receptor (NR) that includes all signaling molecules that function as ligand-binding transcription factors that bind to specific DNA enhancer sequences and upregulate the transcription of CYP genes. Two classes of NRs will be discussed in this chapter. Members of the nuclear hormone receptor (NHR) superfamily to be reviewed include the constitutive androstane receptor (CAR), the pregnane X-receptor (PXR), and the peroxisome prolifera-tor activated receptors (PPARs). A single member of the PAS superfamily, the aryl hydrocarbon receptor (AHR), will also be discussed. [Pg.323]

See other pages where Transcription factors definition is mentioned: [Pg.29]    [Pg.221]    [Pg.83]    [Pg.150]    [Pg.96]    [Pg.935]    [Pg.47]    [Pg.230]    [Pg.109]    [Pg.551]    [Pg.121]    [Pg.53]    [Pg.53]    [Pg.83]    [Pg.337]    [Pg.400]    [Pg.133]    [Pg.139]    [Pg.156]    [Pg.309]    [Pg.311]    [Pg.238]    [Pg.10]    [Pg.643]    [Pg.378]    [Pg.29]    [Pg.61]    [Pg.1316]    [Pg.1321]    [Pg.1322]    [Pg.170]    [Pg.61]    [Pg.666]    [Pg.148]    [Pg.149]    [Pg.22]    [Pg.431]    [Pg.50]    [Pg.233]    [Pg.78]    [Pg.179]    [Pg.12]    [Pg.14]    [Pg.1753]    [Pg.31]    [Pg.50]    [Pg.98]    [Pg.219]   
See also in sourсe #XX -- [ Pg.156 ]



SEARCH



Transcription definition

Transcription factor

Transcriptional factor

© 2024 chempedia.info