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Trans-factors

R Genes Cis Elements, Trans-factors and Signal Transduction Systems in the Lens, Joram Piatigorksy and Peggy S. Zelen-ka, National Eye Institute, National Institutes of Health, Maryland. Subject Index. [Pg.190]

Mutations that stimulate exon 10 inclusion into the human tau mRNA, which is regulated by an intricate interplay of cis elements and trans factors, cause FTDP-17 and other tauopathies. This suggests that the ratio of exon 10 inclusion to exclusion in the adult brain is one of the factors to determine biological functions of the tau protein. [Pg.249]

Grierson, C., Du, J.S., de Torres Zabala, M., Beggs, K., Smith, C., Holdsworth, M., and Bevan, M. (1994). Separate cis sequences and trans factors direct metabolic and developmental regulation of a potato tuber storage protein gene. Plant J. 5(6) 815-826. [Pg.24]

DNA conformation, allowing access of trans-factors to regulatory regions, or alternatively by maintaining close contact between genes and the transcriptional machinery, which is presumed to be located at the basis of chromosomal scaffolds (Jackson, 1986). [Pg.255]

Figure 2 Nucleotide sequence of DOR gene 5 flanking region. Sequence is numbered relative to + 1 representing the A nucleotide in the ATG translation start codon, indicated by bold type. Positions of minor transcription initiation sites determined from estimates of RNase protected fragment sizes are indicated with bullets ( ) The two strongest transcription start sites are indicated by asterisks ( ) at positions —142 and —324. The cis elements and corresponding trans factors that have been identified are underlined and labeled above the sequence, respectively. (From Ref. 16.)... Figure 2 Nucleotide sequence of DOR gene 5 flanking region. Sequence is numbered relative to + 1 representing the A nucleotide in the ATG translation start codon, indicated by bold type. Positions of minor transcription initiation sites determined from estimates of RNase protected fragment sizes are indicated with bullets ( ) The two strongest transcription start sites are indicated by asterisks ( ) at positions —142 and —324. The cis elements and corresponding trans factors that have been identified are underlined and labeled above the sequence, respectively. (From Ref. 16.)...
Figure 3 A schematic representation of the cis elements and corresponding trans factors that have been identified in the mouse DOR promoter. The translation start site (ATG) is designated as + 1. The asterisk ( ) marked transcription factor and its cognate binding site are identified in T cells, with the rest in neuronal cells. The (+ ) and (—) indicate positive and negative effects, respectively. EBS stands for Ets-1-binding site. Figure 3 A schematic representation of the cis elements and corresponding trans factors that have been identified in the mouse DOR promoter. The translation start site (ATG) is designated as + 1. The asterisk ( ) marked transcription factor and its cognate binding site are identified in T cells, with the rest in neuronal cells. The (+ ) and (—) indicate positive and negative effects, respectively. EBS stands for Ets-1-binding site.
Fig. 1 Representative splicing cu-elements and tran -factors. Tissue-specific and developmental stage-specific expressions of splicing trans-factors including SR proteins and hnRNP Al enable precise regulations of alternative splicing. ISE and ISS have similar activities as ESE and ESS, but are omitted firom the figure... Fig. 1 Representative splicing cu-elements and tran -factors. Tissue-specific and developmental stage-specific expressions of splicing trans-factors including SR proteins and hnRNP Al enable precise regulations of alternative splicing. ISE and ISS have similar activities as ESE and ESS, but are omitted firom the figure...

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Trans-acting factors

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