Tramadol advantages

Tramadol has a side-effect profile similar to that of other opioid analgesics. It may also enhance the risk of seizures. It may be useful for treating chronic pain, especially neuropathic pain, but it has little advantage over other opioid analgesics for acute pain. 

Tramadol may have a place in treating patients with chronic pain, especially that of neuropathic origin. However, this agent has little advantage over the previously mentioned opioid analgesics when... 

Because of the possible increased risk of seizures, tramadol should be used with caution in patients taking drugs such as the SSRIs, which can lower the seizure threshold. The concurrent use of tramadol and SSRIs may also lead to an increase in serotonin-associated effects, which can include the serotonin syndrome. However, the relatively few reported cases of the serotonin syndrome or other reactions due to an interaction between an SSRI and tramadol need to be set in the wider context of apparently uneventful and advantageous use in other patients,although some workers have suggested that the incidence of serotonin syndrome may be underreported. There would seem to be little reason for totally avoiding the concur-... 

Because of its dual site of action pharmacology, tramadol is less likely to be associated with mu receptor-mediated respiratory depression, constipation, and abuse when compared to pure mu agonists. These qualities may make this drug choice more advantageous for elderly and high-risk patients with moderate pain. 

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