Toxic load exponent

As stated previously, higher the toxic load exponent, greater the influence that the vapor concentration has on toxicity. The only instance in which the toxic load exponent was not greater... 

Experimentally Determined Toxic Load Exponents for Nerve Agent Vapor in Rat and Swine... 

Endpoint Species Agent Toxic Load Exponent References... 

Figure 5.1 Concentration-exposure time relationship for SM effects on the eyes. Plots of pooled data from human exposures carried out in the and India " based on the model logt = wrlogEC + logK where t is exposure time, EC is the effective concentration, iT is a constant unique to the toxic effect and m is the toxic load exponent. The effects are those described by the authors as minor effect (fine bulbar injection), definite effect (conjunctivitis) and as casualty or just short of casualty (not well defined in the source documents but probably severe conjunctivitis or blepharospasm producing temporary blindness). The similarity of the EC values for conjunctivitis and definite effect probably reflects the poor fit to the data for the former as demonstrated by the lower value for that regression line.

In Eq. (2.54) C(t ) denotes the variation with time of the chlorine concentration. Generally the time integral over a concentration is called dose. However, if an exponent 1 is applied to the concentration we speak of load, e.g. in this case toxic load. 

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